Manager/Director/VP, Biomarkers – Omics, Bioinformatics

Remote, USA Full-time
Job Description: • *What you’ll own:**- Strategy: Define the biomarker roadmap across all major ’omics (methylation/epigenomics, RNA/transcriptomics, proteomics, metabolomics) with high precision and repeatability over time.- Partnerships: Source, vet, and negotiate with labs/CROs/platforms (CLIA/CAP, research-grade), set SLAs, QC bars, batch schedules, and data contracts.- Assay selection & validation: Choose platforms (e.g., EPIC/WGBS, RNA-seq, Olink/SomaScan, targeted LC-MS/GC-MS, as well as emerging tech) and design validation plans (replicates, spike-ins, controls, precision/accuracy, LOD/LOQ).- Pipelines & analytics: Stand up ingestion/QC/normalization pipelines; build longitudinal models (mixed-effects, time-series) to detect true within-person change.- Bioinformatics → product: Translate signals into deployable metrics (risk, trend, response) that power protocols, content, and customer experiences.- Study design & compliance: Architect IRB-appropriate protocols; ensure data governance (HIPAA/PHI), CAP/CLIA awareness for claims, and auditable methods.- Cross-functional leadership: Partner with departments and stakeholders to turn evidence into clear, defensible narratives and user experiences.- Reporting: Oversee the design, improvement, and maintenance of a biomarker performance dashboard (assay QC, turnaround, failure rates, cost per insight) and a living evidence dossier. Requirements: • *Qualifications:**- PhD or MS in bioinformatics, computational biology, systems biology, data science, or related field.- 6–10+ years designing and managing/running multi-omics projects (industry/startup or leading academic core).- Hands-on with: Python/R, SQL; pipeline tooling; cloud warehousing, data storage and processing; Git & containers.- Familiarity with CLIA/CAP contexts, HIPAA/PHI, and evidence standards for consumer-facing health claims.- Excellent communicator who moves smoothly from technical memos to exec-level decisions. Benefits: • *Base Salary: $130-250k** Apply tot his job
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